Crizotinib-induced osteitis mimicking bone metastasis in a stage IV ALK-rearranged NSCLC patient: a case report

Abstract Background Targeted therapies hydrate + a-vitamin are a standard of care for first-line treatment of Anaplastic lymphoma kinase (ALK)-rearranged non small cell lung cancer (NSCLC).Giving the rapid pace of drug discovery and development in this area, reporting of adverse effects of ALK inhibitors is crucial.Here, we report a case of osteiti

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Czech medicinal plants as possible sources of antioxidants

The antioxidant activity of 17 Czech medicinal plants was studied and Display System Hardware compared with the antioxidant activity of green tea.The antioxidant activities of water and ethanol extracts of the plants tested were determined by a spectrophotometric method using the stable free radical DPPH (2,2-diphenyl-1-picrylhydrazyl), and further

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Identification of biomarkers in common chronic lung diseases by co-expression networks and drug-target interactions analysis

Abstract Background asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF) are three serious pulmonary diseases that contain common and unique characteristics.Therefore, the identification of biomarkers that differentiate these diseases is of importance for preventing misdiagnosis.In this regard, the present s

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